Author Archives: Roger

MICROBICIDES: Efficacy and Effectiveness

What is good enough? Who decides?
This presentation was prepared for an IRMA global teleconference on December 4, 2009.

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Microbicides for HIV Prevention

Microbicides are compounds that can be applied inside the vagina or rectum to protect against sexually transmitted infections (STIs) including HIV. They can be formulated as gels, creams, films, or suppositories. Microbicides may or may not have spermicidal activity (contraceptive effect). At present, an effective microbicide is not available (WHO definition)

PrEP, An Overview

Pre-exposure prophylaxis (PrEP) is an experimental HIV-prevention strategy that proposes using antiretrovirals (ARVs) to reduce the risk of HIV infection in healthy uninfected people at risk of acquiring the virus. PrEP is not proven to work and is currently being tested in HIV-negative people in several clinical trials across the world. It is

Barriers to condom use

To use or not to use a condom for sexual intercourse is the result of a combination of several interacting factors. From the rational decision to choose not to use condoms to that of not being able to choose to use them, there is a broad range of possible accounts.
Addressing poor condom use therefore is

A Sustainable Globalisation?

Globalisation has been the buzzword of the roaring nineties and with the fall of the Berlin’s wall, the end of the cold war and the victory of capitalism over socialism it has opened a new era in human history. Rightly or not, globalisation has become synonymous with market economy, capitalism and development. Much discussions, books

Biological Factors Affecting HIV Infection

Several factors are important in determining if the HIV virus can be passed from an infected person to another one. These include biological and social factors which both relate to the exposed and the “infector” individuals.
This conceptual framework summarises only the biological factors that influence HIV transmission. When assessing the risk of infection, each should

Diseases of Poverty

A conceptual framework for understanding the diseases of poverty. Despite tremendous technological and scientific progresses in the understanding of diseases and their management, millions of people in the developing world still die of preventable infections and food scarcity whilst millions of other in the developped world die of diseases of opulence and excess.

HIV Prevention, an Overview

HIV prevention goes far beyond the simplistic ABC message that hijacks most of the media attention. This figure tries to illustrate the breadth and diversity of the field of HIV prevention (Click to enlarge). It would still need to be further expanded to really cover all the aspects of an ever growing field.

The SYFA Website

SYFA (Save Your Future Association) was founded in 2001 by Farmer Tantoh Nforba and is located in Nkambe, North West Province of Cameroon.
SYFA works with local farmers, youths and children on environmental protection, organic agriculture and home gardening and currently coordinates the activities of 10 environmental groups at local schools, churches and the prison
The project

Scientific Publications

Fearnside JF, Dumas ME, Rothwell AR, Wilder SP, Cloarec O, Toye A, Blancher C, Holmes E, Tatoud R, Barton RH, Scott J, Nicholson JK, Gauguier D. Phylometabonomic patterns of adaptation to high fat diet feeding in inbred mice. PLoS ONE 3, e1668 (2008).
Toye AA, Dumas ME, Blancher C, Rothwell AR, Fearnside JF, Wilder SP, Bihoreau